TargetRx Atlas

MRNA basic information

  • mRNA ID:ENST00000341049
  • Gene Name:CAV1
  • mRNA database:Ensembl
  • mRNA expression :down-regulated
  • mRNA Method:RT-PCR
  • mRNA Pathway:Notch-1/Akt/NF-kB
  • Evidence:predicted
  • (mRNA-drug)

Drug basic information

  • Drug ID:NA
  • Drug Name:NA
  • Drug Method:NA

Disease basic infommation

  • Disease:ovarian cancer
  • Tissue:Human ovarian cancer cell lines SKOV3 and A2780 and human cisplatin-resistance ovarian cancer cell lines SKOV3/DDP and A2780/DDP

Other information

  • Title:Caveolin-1 mediates chemoresistance in cisplatin-resistant ovarian cancer cells by targeting apoptosis through the Notch-1/Akt/NF-kBpathway.
  • Journal:Oncology reports
  • Published:2015
  • PubMed ID:26503358
  • Abstract: