|
mRNA_ID
|
Gene Name
|
drug_ID
|
drug_Name
|
Disease
|
RNA_exp_pattern
|
Evidence
|
Details
|
|
ENST00000212015
|
SIRT1
|
DB00331
|
Metformin
|
type 2 diabetes mellitus
|
up-regulated
|
validated
|
more...
|
|
ENST00000225916
|
KAT2A
|
DB00331
|
Metformin
|
type 2 diabetes mellitus
|
up-regulated
|
validated
|
more...
|
|
ENST00000313005
|
BACE1
|
DB00331
|
Metformin
|
alzheimer＇s disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000317552
|
MID1
|
DB00331
|
Metformin
|
alzheimer＇s disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000276914
|
PLIN2
|
DB00331
|
Metformin
|
non-alcoholic fatty liver disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000261796
|
IL17B
|
DB00331
|
Metformin
|
inflammatory bowel disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000648244
|
IL17A
|
DB00331
|
Metformin
|
inflammatory bowel disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000264657
|
STAT3
|
DB00331
|
Metformin
|
inflammatory bowel disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000261796
|
IL17B
|
DB00331
|
Metformin
|
type 2 diabete
|
down-regulated
|
validated
|
more...
|
|
ENST00000648244
|
IL17A
|
DB00331
|
Metformin
|
type 2 diabete
|
down-regulated
|
validated
|
more...
|
|
ENST00000264657
|
STAT3
|
DB00331
|
Metformin
|
type 2 diabete
|
down-regulated
|
validated
|
more...
|
|
ENST00000373471
|
FNDC5
|
DB00331
|
Metformin
|
diabetes
|
up-regulated
|
validated
|
more...
|
|
ENST00000373471
|
FNDC5
|
DB00331
|
Metformin
|
obesity
|
up-regulated
|
validated
|
more...
|
|
ENST00000261769
|
CDH1
|
DB00331
|
Metformin
|
enteritis
|
up-regulated
|
validated
|
more...
|
|
ENST00000395145
|
CLDN3
|
DB00331
|
Metformin
|
enteritis
|
up-regulated
|
validated
|
more...
|
|
ENST00000306011
|
ATOH1
|
DB00331
|
Metformin
|
enteritis
|
up-regulated
|
validated
|
more...
|
|
ENST00000374580
|
BMPR2
|
DB00331
|
Metformin
|
enteritis
|
up-regulated
|
validated
|
more...
|
|
ENST00000245451
|
BMP4
|
DB00331
|
Metformin
|
enteritis
|
up-regulated
|
validated
|
more...
|
|
ENST00000263341
|
IL1B
|
DB00331
|
Metformin
|
enteritis
|
down-regulated
|
validated
|
more...
|
|
ENST00000445232
|
TNF
|
DB00331
|
Metformin
|
enteritis
|
down-regulated
|
validated
|
more...
|
|
ENST00000258743
|
IL6
|
DB00331
|
Metformin
|
enteritis
|
down-regulated
|
validated
|
more...
|
|
ENST00000263025
|
MAPK3
|
DB00331
|
Metformin
|
pancreatic ductal adenocarcinoma
|
down-regulated
|
validated
|
more...
|
|
ENST00000381033
|
PDX1
|
DB00331
|
Metformin
|
pancreatic ductal adenocarcinoma
|
down-regulated
|
validated
|
more...
|
|
ENST00000379561
|
FOXO1
|
DB00331
|
Metformin
|
cancer
|
up-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00331
|
Metformin
|
multiple sclerosis
|
down-regulated
|
validated
|
more...
|
|
ENST00000337138
|
HIF1A
|
DB00331
|
Metformin
|
multiple sclerosis
|
down-regulated
|
validated
|
more...
|
|
ENST00000396290
|
ID2
|
DB00331
|
Metformin
|
breast cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000376112
|
ID1
|
DB00331
|
Metformin
|
breast cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000238682
|
TGFB3
|
DB00331
|
Metformin
|
breast cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000366930
|
TGFB2
|
DB00331
|
Metformin
|
breast cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000221930
|
TGFB1
|
DB00331
|
Metformin
|
breast cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000327367
|
SMAD3
|
DB00331
|
Metformin
|
breast cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000262160
|
SMAD2
|
DB00331
|
Metformin
|
breast cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000308394
|
CASP3
|
DB00331
|
Metformin
|
breast cancer
|
up-regulated
|
validated
|
more...
|
|
ENST00000371244
|
PRKAA2
|
DB00331
|
Metformin
|
breast cancer
|
up-regulated
|
validated
|
more...
|
|
ENST00000302850
|
INSR
|
DB00331
|
Metformin
|
metabolic syndrome
|
up-regulated
|
validated
|
more...
|
|
ENST00000206249
|
ESR1
|
DB00331
|
Metformin
|
metabolic syndrome
|
up-regulated
|
validated
|
more...
|
|
ENST00000392038
|
AKT2
|
DB00331
|
Metformin
|
metabolic syndrome
|
up-regulated
|
validated
|
more...
|
|
ENST00000215832
|
MAPK1
|
DB00331
|
Metformin
|
metabolic syndrome
|
up-regulated
|
validated
|
more...
|
|
ENST00000302850
|
INSR
|
DB00331
|
Metformin
|
polycystic ovary syndrome
|
up-regulated
|
validated
|
more...
|
|
ENST00000206249
|
ESR1
|
DB00331
|
Metformin
|
polycystic ovary syndrome
|
up-regulated
|
validated
|
more...
|
|
ENST00000392038
|
AKT2
|
DB00331
|
Metformin
|
polycystic ovary syndrome
|
up-regulated
|
validated
|
more...
|
|
ENST00000215832
|
MAPK1
|
DB00331
|
Metformin
|
polycystic ovary syndrome
|
up-regulated
|
validated
|
more...
|
|
ENST00000558518
|
LDLR
|
DB00331
|
Metformin
|
diabetes
|
up-regulated
|
validated
|
more...
|
|
ENST00000361204
|
SREBF2
|
DB00331
|
Metformin
|
diabetes
|
down-regulated
|
validated
|
more...
|
|
ENST00000261646
|
SREBF1
|
DB00331
|
Metformin
|
obesity
|
down-regulated
|
validated
|
more...
|
|
ENST00000495186
|
EBP
|
DB00331
|
Metformin
|
obesity
|
down-regulated
|
validated
|
more...
|
|
ENST00000651735
|
PPARG
|
DB00331
|
Metformin
|
obesity
|
down-regulated
|
validated
|
more...
|
|
ENST00000319441
|
PCK1
|
DB00331
|
Metformin
|
diabetes mellitus
|
down-regulated
|
validated
|
more...
|
|
ENST00000379561
|
FOXO1
|
DB00331
|
Metformin
|
diabetes mellitus
|
down-regulated
|
validated
|
more...
|
|
ENST00000253801
|
G6PC1
|
DB00331
|
Metformin
|
diabetes mellitus
|
down-regulated
|
validated
|
more...
|
|
ENST00000262776
|
LGALS3BP
|
DB00331
|
Metformin
|
multiple sclerosis
|
down-regulated
|
validated
|
more...
|
|
ENST00000371244
|
PRKAA2
|
DB00331
|
Metformin
|
multiple sclerosis
|
up-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00331
|
Metformin
|
multiple sclerosis
|
up-regulated
|
validated
|
more...
|
|
ENST00000302850
|
INSR
|
DB00331
|
Metformin
|
polycystic ovary syndrome
|
up-regulated
|
validated
|
more...
|
|
ENST00000392038
|
AKT2
|
DB00331
|
Metformin
|
polycystic ovary syndrome
|
up-regulated
|
validated
|
more...
|
|
ENST00000215832
|
MAPK1
|
DB00331
|
Metformin
|
polycystic ovary syndrome
|
up-regulated
|
validated
|
more...
|
|
ENST00000000442
|
ESRRA
|
DB00331
|
Metformin
|
polycystic ovary syndrome
|
up-regulated
|
validated
|
more...
|
|
ENST00000238994
|
PPP1R3C
|
DB00331
|
Metformin
|
type 2 diabetes
|
down-regulated
|
validated
|
more...
|
|
ENST00000393370
|
PTPA (PPP2R4)
|
DB00331 (APRD01099)
|
Metformin
|
endometrial cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000508803
|
NSD2 (MMSET)
|
DB00331 (APRD01099)
|
Metformin
|
prostate cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000264198
|
MUL1
|
DB00331 (APRD01099)
|
Metformin
|
ovarian cancer
|
up-regulated
|
validated
|
more...
|
|
ENST00000263798
|
TYRO3
|
DB00331 (APRD01099)
|
Metformin
|
ovarian cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000301178
|
AXL
|
DB00331 (APRD01099)
|
Metformin
|
ovarian cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000397062
|
NFE2L2
|
DB00331 (APRD01099)
|
Metformin
|
cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000216117
|
HO1
|
DB00331 (APRD01099)
|
Metformin
|
cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000367858
|
SGK1
|
DB00331 (APRD01099)
|
Metformin
|
breast cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000328827
|
PAR4
|
DB00331 (APRD01099)
|
Metformin
|
breast cancer
|
up-regulated
|
validated
|
more...
|
|
ENST00000341049
|
CAV1
|
DB00331 (APRD01099)
|
Metformin
|
breast cancer
|
up-regulated
|
validated
|
more...
|
|
ENST00000216117
|
HMOX1
|
DB00331 (APRD01099)
|
Metformin
|
breast cancer
|
up-regulated
|
validated
|
more...
|
|
ENST00000346473
|
CHOP
|
DB00331 (APRD01099)
|
Metformin
|
breast cancer
|
up-regulated
|
validated
|
more...
|
|
ENST00000374690
|
AR
|
DB00331 (APRD01099)
|
Metformin
|
prostate cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00331 (APRD01099)
|
Metformin
|
prostate cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000307365
|
REDD1
|
DB00331 (APRD01099)
|
Metformin
|
prostate cancer
|
up-regulated
|
validated
|
more...
|
|
ENST00000206249
|
ESR1 (ER-ALPHA)
|
DB00331 (APRD01099)
|
Metformin
|
endometrial cancer
|
down-regulated
|
validated
|
more...
|