TargetRx Atlas

mRNA_ID Gene Name drug_ID drug_Name Disease RNA_exp_pattern Evidence Details
ENST00000648244 IL-17A DB00169 Vitamin D3 psoriasis up-regulated validated more...
ENST00000651735 PPARG DB00563 Methotrexate psoriasis down-regulated validated more...
ENST00000360694 PPARD DB00563 Methotrexate psoriasis down-regulated validated more...
ENST00000301653 KRT16 DB08877 Ruxolitinib psoriasis down-regulated validated more...
ENST00000368654 MKI67 DB08877 Ruxolitinib psoriasis down-regulated validated more...
ENST00000268296 ITGAX DB08877 Ruxolitinib psoriasis down-regulated validated more...
ENST00000300692 CD3D DB08877 Ruxolitinib psoriasis down-regulated validated more...
ENST00000361763 CD3E DB08877 Ruxolitinib psoriasis down-regulated validated more...
ENST00000304506 IL13 NA Gallein psoriasis up-regulated validated more...
ENST00000274520 IL9 NA Gallein psoriasis up-regulated validated more...
ENST00000231454 IL5 NA Gallein psoriasis up-regulated validated more...
ENST00000231449 IL4 NA Gallein psoriasis up-regulated validated more...
ENST00000215781 OSM NA Gallein psoriasis down-regulated validated more...
ENST00000221978 NKG7 NA Gallein psoriasis down-regulated validated more...
ENST00000203629 LAG3 NA Gallein psoriasis down-regulated validated more...
ENST00000263056 MAP3K8 NA Gallein psoriasis down-regulated validated more...
ENST00000687160 IL18RAP NA Gallein psoriasis down-regulated validated more...
ENST00000392320 STAT4 NA Gallein psoriasis down-regulated validated more...
ENST00000648244 IL17A NA Gallein psoriasis down-regulated validated more...
ENST00000229135 IFNG NA Gallein psoriasis down-regulated validated more...
ENST00000232424 HES1 DB05679 Ustekinumab psoriasis down-regulated validated more...
ENST00000254958 E2F1 DB05679 Ustekinumab psoriasis down-regulated validated more...
ENST00000256646 NOTCH2 DB05679 Ustekinumab psoriasis down-regulated validated more...
ENST00000651671 NOTCH1 DB05679 Ustekinumab psoriasis down-regulated validated more...
ENST00000228534 IL23A DB05679 Ustekinumab psoriasis down-regulated validated more...
ENST00000231228 IL12B DB05679 Ustekinumab psoriasis down-regulated validated more...
ENST00000699704 IL12A DB05679 Ustekinumab psoriasis down-regulated validated more...
ENST00000232424 HES1 DB00051 Adalimumab psoriasis down-regulated validated more...
ENST00000254958 E2F1 DB00051 Adalimumab psoriasis down-regulated validated more...
ENST00000256646 NOTCH2 DB00051 Adalimumab psoriasis down-regulated validated more...
ENST00000651671 NOTCH1 DB00051 Adalimumab psoriasis down-regulated validated more...
ENST00000445232 TNF DB00051 Adalimumab psoriasis down-regulated validated more...
ENST00000232424 HES1 DB00005 Etanercept psoriasis down-regulated validated more...
ENST00000254958 E2F1 DB00005 Etanercept psoriasis down-regulated validated more...
ENST00000256646 NOTCH2 DB00005 Etanercept psoriasis down-regulated validated more...
ENST00000651671 NOTCH1 DB00005 Etanercept psoriasis down-regulated validated more...
ENST00000445232 TNF DB00005 Etanercept psoriasis down-regulated validated more...
ENST00000533400 CASP1 DB00563 Methotrexate psoriasis down-regulated validated more...
ENST00000280357 IL18 DB00563 Methotrexate psoriasis down-regulated validated more...
ENST00000445232 TNF DB00563 Methotrexate psoriasis down-regulated validated more...
ENST00000651735 PPARG NA GSK3787 psoriasis down-regulated validated more...
ENST00000445232 TNF DB00051 Adalimumab psoriasis down-regulated validated more...
ENST00000336123 IL17F DB13105 Resolvin E1 psoriasis down-regulated validated more...
ENST00000682841 IL17D DB13105 Resolvin E1 psoriasis down-regulated validated more...
ENST00000244241 IL17C DB13105 Resolvin E1 psoriasis down-regulated validated more...
ENST00000648244 IL17A DB13105 Resolvin E1 psoriasis down-regulated validated more...
ENST00000261796 IL17B DB13105 Resolvin E1 psoriasis down-regulated validated more...
ENST00000228534 IL23A DB13105 Resolvin E1 psoriasis down-regulated validated more...
ENST00000264832 ICAM1 NA Sancao Formula psoriasis down-regulated validated more...
ENST00000451137 CCN1 NA Sancao Formula psoriasis down-regulated validated more...
ENST00000241052 CAT DB01188 Ciclopirox psoriasis up-regulated validated more...
ENST00000270142 SOD1 DB01188 Ciclopirox psoriasis up-regulated validated more...
ENST00000487519 TFAM DB01188 Ciclopirox psoriasis up-regulated validated more...
ENST00000397062 NFE2L2 DB01188 Ciclopirox psoriasis up-regulated validated more...
ENST00000393232 NRF1 DB01188 Ciclopirox psoriasis up-regulated validated more...
ENST00000371953 PTEN DB02656 LY-294002 psoriasis up-regulated validated more...
ENST00000648244 IL17A DB02656 LY-294002 psoriasis down-regulated validated more...
ENST00000312629 RPS6KB2 DB02656 LY-294002 psoriasis down-regulated validated more...
ENST00000225577 RPS6KB1 DB02656 LY-294002 psoriasis down-regulated validated more...
ENST00000361445 MTOR DB02656 LY-294002 psoriasis down-regulated validated more...
ENST00000649815 AKT1 DB02656 LY-294002 psoriasis down-regulated validated more...
ENST00000232424 HES1 DB02656 LY-294002 psoriasis down-regulated validated more...
ENST00000651671 NOTCH1 DB02656 LY-294002 psoriasis down-regulated validated more...
ENST00000349243 AGTR1 DB00678 Losartan psoriasis down-regulated validated more...
ENST00000371906 AGTR2 DB00678 Losartan psoriasis down-regulated validated more...
ENST00000228534 IL23A DB00678 Losartan psoriasis down-regulated validated more...
ENST00000648244 IL17A DB00678 Losartan psoriasis down-regulated validated more...
ENST00000445232 TNF DB00678 Losartan psoriasis down-regulated validated more...
ENST00000228534 IL23A NA HSP90 inhibitor RGRN-305 psoriasis down-regulated validated more...
ENST00000258743 IL6 NA HSP90 inhibitor RGRN-305 psoriasis down-regulated validated more...
ENST00000263341 IL1B NA HSP90 inhibitor RGRN-305 psoriasis down-regulated validated more...
ENST00000383496 TNF NA HSP90 inhibitor RGRN-305 psoriasis down-regulated validated more...
ENST00000259205 IL36G NA HSP90 inhibitor RGRN-305 psoriasis down-regulated validated more...
ENST00000641389 NFKBID NA HSP90 inhibitor RGRN-305 psoriasis down-regulated validated more...
ENST00000326172 NFKBIZ NA HSP90 inhibitor RGRN-305 psoriasis down-regulated validated more...
ENST00000358813 CCL20 NA HSP90 inhibitor RGRN-305 psoriasis down-regulated validated more...
ENST00000258743 IL6 DB00005 Etanercept psoriasis down-regulated validated more...
ENST00000229135 IFNG DB15584 Luteolin psoriasis down-regulated validated more...
ENST00000299767 HSP90B1 DB15584 Luteolin psoriasis down-regulated validated more...
ENST00000216281 HSP90AA1 DB15584 Luteolin psoriasis down-regulated validated more...
ENST00000263341 IL1B DB11672 Curcumin psoriasis down-regulated validated more...
ENST00000336123 IL17F DB11672 Curcumin psoriasis down-regulated validated more...
ENST00000648244 IL17A DB11672 Curcumin psoriasis down-regulated validated more...
ENST00000449264 TNF DB11672 Curcumin psoriasis down-regulated validated more...
ENST00000538666 IL22 DB11672 Curcumin psoriasis down-regulated validated more...
@Copyright Harbin Medical University
　The 2nd Affiliated Hospital of Harbin Medical University
　 备案号：鲁ICP备2022025566号-3