|
mRNA_ID
|
Gene Name
|
drug_ID
|
drug_Name
|
Disease
|
RNA_exp_pattern
|
Evidence
|
Details
|
|
ENST00000254976
|
SNAP25
|
DB00877
|
Sirolimus
|
type 2 diabetes
|
down-regulated
|
validated
|
more...
|
|
ENST00000316509
|
VAMP2
|
DB00877
|
Sirolimus
|
type 2 diabetes
|
down-regulated
|
validated
|
more...
|
|
ENST00000278379
|
SLC1A2
|
DB00877
|
Sirolimus
|
amyotrophic lateral sclerosis
|
down-regulated
|
validated
|
more...
|
|
ENST00000278379
|
SLC1A2
|
DB00877
|
Sirolimus
|
alzheimer＇s disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000278379
|
SLC1A2
|
DB00877
|
Sirolimus
|
stroke
|
down-regulated
|
validated
|
more...
|
|
ENST00000224784
|
ACTA2
|
DB00877
|
Sirolimus
|
chronic obstructive pulmonary disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000354785
|
FN1
|
DB00877
|
Sirolimus
|
chronic obstructive pulmonary disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000304636
|
COL3A1
|
DB00877
|
Sirolimus
|
chronic obstructive pulmonary disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000225964
|
COL1A1
|
DB00877
|
Sirolimus
|
chronic obstructive pulmonary disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000295400
|
TGFA
|
DB00877
|
Sirolimus
|
chronic obstructive pulmonary disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000239938
|
EGR1
|
DB00877
|
Sirolimus
|
chronic obstructive pulmonary disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000224784
|
ACTA2
|
DB00877
|
Sirolimus
|
asthma
|
down-regulated
|
validated
|
more...
|
|
ENST00000354785
|
FN1
|
DB00877
|
Sirolimus
|
asthma
|
down-regulated
|
validated
|
more...
|
|
ENST00000304636
|
COL3A1
|
DB00877
|
Sirolimus
|
asthma
|
down-regulated
|
validated
|
more...
|
|
ENST00000225964
|
COL1A1
|
DB00877
|
Sirolimus
|
asthma
|
down-regulated
|
validated
|
more...
|
|
ENST00000295400
|
TGFA
|
DB00877
|
Sirolimus
|
asthma
|
down-regulated
|
validated
|
more...
|
|
ENST00000239938
|
EGR1
|
DB00877
|
Sirolimus
|
asthma
|
down-regulated
|
validated
|
more...
|
|
ENST00000392038
|
AKT2
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000649815
|
AKT1
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000238682
|
TGFB3
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000366930
|
TGFB2
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000221930
|
TGFB1
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
hyperthyroidism
|
down-regulated
|
validated
|
more...
|
|
ENST00000395826
|
POMC
|
DB00877
|
Sirolimus
|
hyperthyroidism
|
up-regulated
|
validated
|
more...
|
|
ENST00000450525
|
THRA
|
DB00877
|
Sirolimus
|
hyperthyroidism
|
up-regulated
|
validated
|
more...
|
|
ENST00000356613
|
ARC
|
DB00877
|
Sirolimus
|
hyperthyroidism
|
up-regulated
|
validated
|
more...
|
|
ENST00000242152
|
NPY
|
DB00877
|
Sirolimus
|
hyperthyroidism
|
down-regulated
|
validated
|
more...
|
|
ENST00000290953
|
AGRP
|
DB00877
|
Sirolimus
|
hyperthyroidism
|
down-regulated
|
validated
|
more...
|
|
ENST00000450253
|
EIF4E
|
DB00877
|
Sirolimus
|
inflammation
|
down-regulated
|
validated
|
more...
|
|
ENST00000338825
|
EIF4EBP1
|
DB00877
|
Sirolimus
|
inflammation
|
down-regulated
|
validated
|
more...
|
|
ENST00000445232
|
TNF
|
DB00877
|
Sirolimus
|
inflammation
|
down-regulated
|
validated
|
more...
|
|
ENST00000258743
|
IL6
|
DB00877
|
Sirolimus
|
inflammation
|
down-regulated
|
validated
|
more...
|
|
ENST00000650385
|
FCGR3B
|
DB00877
|
Sirolimus
|
inflammation
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
inflammation
|
down-regulated
|
validated
|
more...
|
|
ENST00000225577
|
RPS6KB1
|
DB00877
|
Sirolimus
|
inflammation
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
vascular calcification
|
down-regulated
|
validated
|
more...
|
|
ENST00000225577
|
RPS6KB1
|
DB00877
|
Sirolimus
|
vascular calcification
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
non-alcoholic fatty liver disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000447544
|
CD36
|
DB00877
|
Sirolimus
|
non-alcoholic fatty liver disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
septicemia
|
down-regulated
|
validated
|
more...
|
|
ENST00000297904
|
VEGFD
|
DB00877
|
Sirolimus
|
choroidal vascular disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000618562
|
VEGFC
|
DB00877
|
Sirolimus
|
choroidal vascular disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000309422
|
VEGFB
|
DB00877
|
Sirolimus
|
choroidal vascular disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000672860
|
VEGFA
|
DB00877
|
Sirolimus
|
choroidal vascular disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000337138
|
HIF1A
|
DB00877
|
Sirolimus
|
choroidal vascular disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
choroidal vascular disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000219476
|
TSC2
|
DB00877
|
Sirolimus
|
tuberous sclerosis complex related tumor
|
down-regulated
|
validated
|
more...
|
|
ENST00000298552
|
TSC1
|
DB00877
|
Sirolimus
|
tuberous sclerosis complex related tumor
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
tuberous sclerosis complex related tumor
|
down-regulated
|
validated
|
more...
|
|
ENST00000221930
|
TGFB1
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000394236
|
PROS1
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000264832
|
ICAM1
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000225831
|
CCL2
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000263341
|
IL1B
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000225831
|
CCL2
|
DB00877
|
Sirolimus
|
chronic kidney disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000376207
|
FOXP3
|
DB00877
|
Sirolimus
|
acute kidney injury
|
up-regulated
|
validated
|
more...
|
|
ENST00000221930
|
TGFB1
|
DB00877
|
Sirolimus
|
acute kidney injury
|
up-regulated
|
validated
|
more...
|
|
ENST00000675419
|
RUNX1
|
DB00877
|
Sirolimus
|
acute kidney injury
|
down-regulated
|
validated
|
more...
|
|
ENST00000229135
|
IFNG
|
DB00877
|
Sirolimus
|
acute kidney injury
|
down-regulated
|
validated
|
more...
|
|
ENST00000258743
|
IL6
|
DB00877
|
Sirolimus
|
acute kidney injury
|
down-regulated
|
validated
|
more...
|
|
ENST00000263341
|
IL1B
|
DB00877
|
Sirolimus
|
acute kidney injury
|
down-regulated
|
validated
|
more...
|
|
ENST00000318507
|
CXCR2
|
DB00877
|
Sirolimus
|
acute kidney injury
|
down-regulated
|
validated
|
more...
|
|
ENST00000508487
|
CXCL2
|
DB00877
|
Sirolimus
|
acute kidney injury
|
down-regulated
|
validated
|
more...
|
|
ENST00000395761
|
CXCL1
|
DB00877
|
Sirolimus
|
acute kidney injury
|
down-regulated
|
validated
|
more...
|
|
ENST00000313735
|
NOS2
|
DB00877
|
Sirolimus
|
epilepsy
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
epilepsy
|
down-regulated
|
validated
|
more...
|
|
ENST00000313735
|
NOS2
|
DB00877
|
Sirolimus
|
neuroinflammation
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
neuroinflammation
|
down-regulated
|
validated
|
more...
|
|
ENST00000374259
|
FOXO4
|
DB00877
|
Sirolimus
|
vascular smooth muscle injury
|
down-regulated
|
validated
|
more...
|
|
ENST00000392038
|
AKT2
|
DB00877
|
Sirolimus
|
vascular smooth muscle injury
|
down-regulated
|
validated
|
more...
|
|
ENST00000649815
|
AKT1
|
DB00877
|
Sirolimus
|
vascular smooth muscle injury
|
down-regulated
|
validated
|
more...
|
|
ENST00000648244
|
IL17A
|
DB00877
|
Sirolimus
|
multiple sclerosis
|
down-regulated
|
validated
|
more...
|
|
ENST00000261796
|
IL17B
|
DB00877
|
Sirolimus
|
multiple sclerosis
|
down-regulated
|
validated
|
more...
|
|
ENST00000229135
|
IFNG
|
DB00877
|
Sirolimus
|
multiple sclerosis
|
down-regulated
|
validated
|
more...
|
|
ENST00000264657
|
STAT3
|
DB00877
|
Sirolimus
|
multiple sclerosis
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
multiple sclerosis
|
down-regulated
|
validated
|
more...
|
|
ENST00000674920
|
ATF4
|
DB00877
|
Sirolimus
|
multiple myeloma
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
intractable epilepsy
|
down-regulated
|
validated
|
more...
|
|
ENST00000281708
|
FBXW7
|
DB00877
|
Sirolimus
|
non small cell lung cancer
|
up-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
diabetic pregnancy
|
down-regulated
|
validated
|
more...
|
|
ENST00000590099
|
BECN1
|
DB00877
|
Sirolimus
|
catagma
|
down-regulated
|
validated
|
more...
|
|
ENST00000338825
|
EIF4EBP1
|
DB00877
|
Sirolimus
|
left ventricular hypertrophy
|
down-regulated
|
validated
|
more...
|
|
ENST00000225577
|
RPS6KB1
|
DB00877
|
Sirolimus
|
left ventricular hypertrophy
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
left ventricular hypertrophy
|
down-regulated
|
validated
|
more...
|
|
ENST00000372330
|
MMP9
|
DB00877
|
Sirolimus
|
left ventricular hypertrophy
|
down-regulated
|
validated
|
more...
|
|
ENST00000355349
|
MYH7
|
DB00877
|
Sirolimus
|
left ventricular hypertrophy
|
down-regulated
|
validated
|
more...
|
|
ENST00000376480
|
NPPA
|
DB00877
|
Sirolimus
|
left ventricular hypertrophy
|
down-regulated
|
validated
|
more...
|
|
ENST00000282077
|
PDK1
|
DB00877
|
Sirolimus
|
acute lymphocytic leukemia
|
up-regulated
|
validated
|
more...
|
|
ENST00000290573
|
HK2
|
DB00877
|
Sirolimus
|
acute lymphocytic leukemia
|
up-regulated
|
validated
|
more...
|
|
ENST00000306434
|
MAT2A
|
DB00877
|
Sirolimus
|
acute lymphocytic leukemia
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
pulmonary arterial hypertension
|
down-regulated
|
validated
|
more...
|
|
ENST00000445232
|
TNF
|
DB00877
|
Sirolimus
|
spondyloarthritis
|
down-regulated
|
validated
|
more...
|
|
ENST00000648244
|
IL17A
|
DB00877
|
Sirolimus
|
spondyloarthritis
|
down-regulated
|
validated
|
more...
|
|
ENST00000318247
|
RORC
|
DB00877
|
Sirolimus
|
airway inflammation
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
airway inflammation
|
down-regulated
|
validated
|
more...
|
|
ENST00000318247
|
RORC
|
DB00877
|
Sirolimus
|
emphysema
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
emphysema
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877
|
Sirolimus
|
glomerulosclerosis
|
down-regulated
|
validated
|
more...
|
|
ENST00000327367
|
SMAD3
|
DB00877
|
Sirolimus
|
glomerulosclerosis
|
down-regulated
|
validated
|
more...
|
|
ENST00000221930
|
TGFB1
|
DB00877
|
Sirolimus
|
glomerulosclerosis
|
down-regulated
|
validated
|
more...
|
|
ENST00000298910
|
LRRK2
|
DB00877 (APRD00178, DB02439)
|
Sirolimus
|
parkinson＇s disease
|
down-regulated
|
validated
|
more...
|
|
ENST00000306336
|
Hcrcn81
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
colorectal cancer
|
up-regulated
|
validated
|
more...
|
|
ENST00000333681
|
BCL2
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
hepatocellular carcinoma
|
down-regulated
|
validated
|
more...
|
|
ENST00000345358
|
BAX
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
hepatocellular carcinoma
|
up-regulated
|
validated
|
more...
|
|
ENST00000244741
|
CDKN1A (P21)
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
hepatocellular carcinoma
|
up-regulated
|
validated
|
more...
|
|
ENST00000228872
|
CDKN1B (P27)
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
hepatocellular carcinoma
|
up-regulated
|
validated
|
more...
|
|
ENST00000269305
|
TP53
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
hepatocellular carcinoma
|
up-regulated
|
validated
|
more...
|
|
ENST00000367468
|
PTGS2
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
ewing sarcoma
|
down-regulated
|
validated
|
more...
|
|
ENST00000361445
|
MTOR
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
osteosarcoma
|
down-regulated
|
validated
|
more...
|
|
ENST00000672860
|
VEGF
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
chronic myeloid leukemia
|
down-regulated
|
validated
|
more...
|
|
ENST00000324642
|
TERT
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
T cell lymphoma
|
down-regulated
|
validated
|
more...
|
|
ENST00000618562
|
VEGFC
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
pancreatic cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000310581
|
TERT
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
endometrial cancer
|
down-regulated
|
validated
|
more...
|
|
ENST00000242261
|
TWIST1
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
cholangiocarcinoma
|
down-regulated
|
validated
|
more...
|
|
ENST00000219070
|
MMP2
|
DB00877 (APRD00178, DB02439)
|
Sirolimus(Rapamycin)
|
cholangiocarcinoma
|
down-regulated
|
validated
|
more...
|