TargetRx Atlas

MRNA basic information

  • mRNA ID:ENST00000337138
  • Gene Name:HIF1A
  • mRNA database:Ensembl
  • mRNA expression :down-regulated
  • mRNA Method:RT-PCR
  • mRNA Pathway:PI-3K/Akt and p42/p44 MAPK signaling pathway
  • Evidence:validated
  • (mRNA-drug)

Drug basic information

  • Drug ID:DB02709 (EXPT02968)
  • Drug Name:Resveratrol
  • Drug Method:promoting the degradation of the protein

Disease basic infommation

  • Disease:tongue carcinoma
  • Tissue:cell lines (SCC-9,HepG2)

Other information

  • Title:Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells
  • Journal:Mol Cancer Ther
  • Published:2005
  • PubMed ID:16227395
  • Abstract:Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells
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