TargetRx Atlas

MRNA basic information

  • mRNA ID:ENST00000212015
  • Gene Name:SIRT1
  • mRNA database:Ensembl
  • mRNA expression :down-regulated
  • mRNA Method:qPCR
  • mRNA Pathway:SIRT1/PGC-1α axis
  • Evidence:validated
  • (mRNA-drug)

Drug basic information

  • Drug ID:DB02709
  • Drug Name:Resveratrol
  • Drug Method:down-regulated the gene expression

Disease basic infommation

  • Disease:high-fat diets
  • Tissue:

Other information

  • Title:Resveratrol protects against a high-fat diet-induced neuroinflammation by suppressing mitochondrial fission via targeting SIRT1/PGC-1α
  • Journal:Experimental Neurology
  • Published:2024
  • PubMed ID:39059737
  • Abstract:
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