TargetRx Atlas

MRNA basic information

  • mRNA ID:ENST00000212015
  • Gene Name:SIRT1
  • mRNA database:Ensembl
  • mRNA expression :up-regulated
  • mRNA Method:qRT-PCR
  • mRNA Pathway:α2-AR/SIRT1/PGC-1α pathway
  • Evidence:validated
  • (mRNA-drug)

Drug basic information

  • Drug ID:DB00633
  • Drug Name:Dexmedetomidine
  • Drug Method:up-regulated the gene expression

Disease basic infommation

  • Disease:sepsis-associated acute kidney injury
  • Tissue:

Other information

  • Title:Dexmedetomidine ameliorates acute kidney injury by regulating mitochondrial dynamics via the α2-AR/SIRT1/PGC-1α pathway activation in rats
  • Journal:Molecular Medicine
  • Published:2024
  • PubMed ID:39455916
  • Abstract:
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