TargetRx Atlas

MRNA basic information

  • mRNA ID:ENST00000212015
  • Gene Name:SIRT1
  • mRNA database:Ensembl
  • mRNA expression :up-regulated
  • mRNA Method:RT-PCR
  • mRNA Pathway:NA
  • Evidence:predicted
  • (mRNA-drug)

Drug basic information

  • Drug ID:NA
  • Drug Name:NA
  • Drug Method:NA

Disease basic infommation

  • Disease:colon cancer
  • Tissue:The human colon cancer cell line HCT116 (Duke’s type D), its isogenic derivative HCT116 p53 +/+ and LS180 (Duke’s type B)

Other information

  • Title:NAMPT?Is a Potent Oncogene in Colon Cancer Progression that Modulates Cancer Stem Cell Properties and Resistance to Therapy through Sirt1 and PARP
  • Journal:Clin Cancer Res.
  • Published:2018
  • PubMed ID:29203587
  • Abstract:
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