TargetRx Atlas

MRNA basic information

  • mRNA ID:ENST00000212015
  • Gene Name:SIRT1
  • mRNA database:Ensembl
  • mRNA expression :up-regulated
  • mRNA Method:RT-PCR
  • mRNA Pathway:NA
  • Evidence:predicted
  • (mRNA-drug)

Drug basic information

  • Drug ID:NA
  • Drug Name:NA
  • Drug Method:NA

Disease basic infommation

  • Disease:lung cancer
  • Tissue:human normal lung (WI38) and 8 non-small cell lung cancer (NSCLC) cell lines

Other information

  • Title:Shikonin induces apoptosis of lung cancer cells via activation of FOXO3a/EGR1/SIRT1 signaling antagonized by p300.
  • Journal:Biochimica et biophysica acta
  • Published:2016
  • PubMed ID:27452907
  • Abstract: