TargetRx Atlas

MRNA basic information

  • mRNA ID:ENST00000212015
  • Gene Name:SIRT1
  • mRNA database:Ensembl
  • mRNA expression :down-regulated
  • mRNA Method:qRT-PCR
  • mRNA Pathway:SIRT1/p53 signaling pathway
  • Evidence:validated
  • (mRNA-drug)

Drug basic information

  • Drug ID:NA
  • Drug Name:YM155
  • Drug Method:down-regulated the gene expression the gene expression

Disease basic infommation

  • Disease:acute lymphoblastic leukemia
  • Tissue:cell line (MOLT-4)

Other information

  • Title:Emerging Effects of Sepantronium Bromide (YM155) on MOLT-4 Cell Line Apoptosis Induction and Expression of Critical Genes Involved in Apoptotic Pathways
  • Journal:Adv Pharm Bull
  • Published:2020
  • PubMed ID:32002365
  • Abstract:
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