TargetRx Atlas

MRNA basic information

  • mRNA ID:ENST00000258743
  • Gene Name:IL-6
  • mRNA database:Ensembl
  • mRNA expression :down-regulated
  • mRNA Method:RT-PCR
  • mRNA Pathway:TNFA signaling pathway
  • Evidence:validated
  • (mRNA-drug)

Drug basic information

  • Drug ID:DB04115
  • Drug Name:Berberine
  • Drug Method:down-regulated the gene expression

Disease basic infommation

  • Disease:atherosclerosis
  • Tissue:cell lines (THP-1)

Other information

  • Title:Berberine inhibits the expression of TNFalpha, MCP-1, and IL-6 in AcLDL-stimulated macrophages through PPARgamma pathway.
  • Journal:Endocrine
  • Published:2008
  • PubMed ID:19034703
  • Abstract:
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